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Categorized List with Citations

Cancers

Blood cancer Research:

Sayiner, S., et al. (2020). Potential risk of certain cancers among patients with Periodontitis: A follow-up study based on meta-analysis. International Journal of Medical Sciences. Linkhttps://www.medsci.org/v17p2531.htm

Assessment of the association between periodontal disease and breast cancer: a systematic review and meta-analysis. (2022). Frontiers in Oncology. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9648345/ (Note: Includes hematologic cancers like blood cancer in broader analyses.)

Breast cancer Research:

Shao, J., et al. (2018). Periodontal Disease and Breast Cancer: A Meta-Analysis of 173,162 Participants and 7,487 Cases. Frontiers in Oncology. Linkhttps://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2018.00601/full

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Cervical cancer Research:

Wang, Y., et al. (2024). Linking periodontitis with 20 cancers, emphasis on oropharyngeal cancer: a Mendelian randomization study. Scientific Reports. Linkhttps://www.nature.com/articles/s41598-024-63447-4

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Colorectal cancer Research:

Xie, M., et al. (2024). The relationship between periodontal disease and cancer: An umbrella review of systematic reviews and meta-analyses. Cancer Causes & Control. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Association between Periodontal Diseases and the Risk of Site-Specific Gastrointestinal Cancers: A Systematic Review and Meta-Analysis. (2024). Journal of Dental Research. Linkhttps://journals.sagepub.com/doi/abs/10.1177/00220345241263768

Esophageal cancer Research:

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Head and neck cancer Research:

Zeng, X. T., et al. (2013). Periodontal disease and the risk of head and neck cancer: a meta-analysis of case-control studies. PLOS ONE. Linkhttps://onlinelibrary.wiley.com/doi/10.1111/prd.12599?af=R

Periodontal Diseases as Putative Risk Factors for Head and Neck Cancer: Systematic Review and Meta-Analysis. (2020). Cancers. Linkhttps://www.mdpi.com/2072-6694/12/7/1893

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Hepatocellular carcinoma Research:

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Kidney cancer Research:

Is periodontal disease a risk indicator for urogenital cancer? A systematic review and meta-analysis. (2022). Frontiers in Oncology. Linkhttps://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.697399/full

Potential risk of certain cancers among patients with Periodontitis. (2020). International Journal of Medical Sciences. Linkhttps://www.medsci.org/v17p2531.htm

Is periodontal disease a risk indicator for urogenital cancer? A systematic review and meta-analysis. (2022). PMC - NIH. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9395701/

Langerhans cell histiocytosis Research:

Papapanou, P. N., et al. (2018). Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop. Journal of Clinical Periodontology. Linkhttps://pubmed.ncbi.nlm.nih.gov/29926943/

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742 (Note: Rare neoplasms discussed in broader reviews.)

Leukemia Research:

Assessment of the association between periodontal disease and breast cancer: a systematic review and meta-analysis. (2022). Frontiers in Oncology. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9648345/ (Note: Broader cancer meta-analysis encompassing blood cancers.)

Lung cancer Research:

Michaud, D. S., et al. (2017). Periodontal Disease, Tooth Loss, and Cancer Risk. Epidemiologic Reviews. Linkhttps://pubmed.ncbi.nlm.nih.gov/28449041/

Relationship between periodontal disease and lung cancer: A systematic review and meta-analysis. (2020). Journal of Periodontal Research. Linkhttps://onlinelibrary.wiley.com/doi/10.1111/jre.12772

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Lymphoma Research:

Non-Hodgkin lymphoma Research:

Assessment of the association between periodontal disease and breast cancer: a systematic review and meta-analysis. (2022). Frontiers in Oncology. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9648345/ (Note: Includes non-Hodgkin lymphoma in hematologic cancer discussions.)

Oral cancer Research:

Li, S., et al. (2024). Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies. Acta Odontologica Scandinavica. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11302657/

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Periodontal Diseases as Putative Risk Factors for Head and Neck Cancer: Systematic Review and Meta-Analysis. (2020). Cancers. Linkhttps://www.mdpi.com/2072-6694/12/7/1893

Oral squamous cell carcinoma Research:

Li, S., et al. (2024). Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies. Acta Odontologica Scandinavica. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11302657/

Association between periodontal disease and oral squamous cell carcinoma: a systematic review and meta-analysis. (2023). British Journal of Oral and Maxillofacial Surgery. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S0266435623001377

Oropharyngeal cancer Research:

Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies. (2024). Acta Odontologica Scandinavica. Linkhttps://medicaljournalssweden.se/actaodontologica/article/view/40478/46205

Pancreatic cancer Research:

Michaud, D. S., et al. (2017). Periodontal Disease, Tooth Loss, and Cancer Risk. Epidemiologic Reviews. Linkhttps://pubmed.ncbi.nlm.nih.gov/28449041/

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Periodontal disease, edentulism, and pancreatic cancer: a meta-analysis. (2013). Annals of Oncology. Linkhttps://www.annalsofoncology.org/article/S0923-7534%2819%2932001-0/fulltext

Prostate cancer Research:

Periodontal disease and prostate cancer: a systematic review and meta-analysis. (2025). Urología Colombiana. Linkhttps://urologiacolombiana.com/en/2025-en/periodontal-disease-and-prostate-cancer-a-systematic-review-and-meta-analysis/

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Secondary metastatic neoplasms Research:

The relationship between periodontal disease and cancer. (2024). Cancer Epidemiology. Linkhttps://www.sciencedirect.com/science/article/abs/pii/S1877782124000742

Tongue cancer Research:

Demystifying the link between periodontitis and oral cancer. (2025). Cancer and Metastasis Reviews. Linkhttps://link.springer.com/article/10.1007/s10555-025-10285-z

Is there a relationship between periodontal disease and oral cancer? A systematic review of currently available evidence. (2016). Critical Reviews in Oncology/Hematology. Linkhttps://www.sciencedirect.com/science/article/pii/S1040842815300330

A Crucial Link Between Periodontal Diseases and Oral Cancer. (2022). Frontiers in Microbiology. Linkhttps://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.919633/full

A Systematic Review and Meta-Analysis Assessing the Role of Oral Health as a Risk Factor in Oral Cancer. (2023). Cureus. Linkhttps://www.cureus.com/articles/160778-a-systematic-review-and-meta-analysis-assessing-the-role-of-oral-health-as-a-risk-factor-in-oral-cancer.pdf

Upper Gastrointestinal cancer Research:

Association between Periodontal Diseases and the Risk of Site-Specific Gastrointestinal Cancers: A Systematic Review and Meta-Analysis. (2024). PubMed. Linkhttps://pubmed.ncbi.nlm.nih.gov/39185624/

Periodontal disease and gastric and colorectal cancers. (2025). Frontiers in Cellular and Infection Microbiology. Linkhttps://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1699738/full

Oral Health and Risk of Upper Gastrointestinal Cancers in a Large Prospective Study. (2021). Cancer Prevention Research. Linkhttps://aacrjournals.org/cancerpreventionresearch/article/14/7/709/666511/Oral-Health-and-Risk-of-Upper-Gastrointestinal

Reproductive

Female infertility Research:

Machado, V., et al. (2022). Periodontitis, female fertility and conception (Review). Biomedical Reports. Linkhttps://www.spandidos-publications.com/10.3892/br.2022.1569

Comparisons of Periodontal Status between Females Referenced for Fertility Treatment and Fertile Counterparts: A Pilot Case–Control Study. (2020). International Journal of Environmental Research and Public Health. Linkhttps://www.mdpi.com/1660-4601/17/15/5281

No association between the presence of periodontal disease and poor IVF outcomes: a pilot study. (2019). International Journal of Women's Health. Linkhttps://www.tandfonline.com/doi/full/10.2147/IJWH.S202135

Gestational hypertensive disorders (pre-eclampsia) Research:

Machado, V., et al. (2022). Periodontitis, female fertility and conception (Review). Biomedical Reports. Linkhttps://www.spandidos-publications.com/10.3892/br.2022.1569

How periodontal diseases affect women's health at different stages of life. (2025). European Federation of Periodontology. Linkhttps://www.efp.org/publications-hub/how-periodontal-diseases-affect-womens-health-at-different-stages-of-life/

Validity of the association between periodontitis and female infertility conditions: a concise review. (2020). Reproduction. Linkhttps://rep.bioscientifica.com/view/journals/rep/160/3/REP-20-0176.xml

Impotence Research:

The Association Between Periodontitis and Erectile Dysfunction. (2021). American Journal of Men's Health. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8142012/

The association between periodontitis and erectile dysfunction: how can periodontists help improve men's health? (2025). European Federation of Periodontology. Linkhttps://www.efp.org/publications-hub/the-association-between-periodontitis-and-erectile-dysfunction-how-can-periodontists-help-improve-mens-health/

Association Between Periodontal Disease and Erectile Dysfunction. (2016). American Journal of Men's Health. Linkhttps://pubmed.ncbi.nlm.nih.gov/27030114/

The Association Between Periodontitis and Erectile Dysfunction. (2021). Sage Journals. Linkhttps://journals.sagepub.com/doi/abs/10.1177/15579883211007277

Low birth weight Research:

Machado, V., et al. (2022). Periodontitis, female fertility and conception (Review). Biomedical Reports. Linkhttps://www.spandidos-publications.com/10.3892/br.2022.1569

Periodontitis and Infertility: An Evidence-Based Review. (2019). Global Journal of Fertility and Research. Linkhttps://www.reprodgroup.us/articles/GJFR-1-103.php

Male infertility Research:

Exploring the link between periodontal disease and sperm quality: a comprehensive systematic review study. (2025). BMC Oral Health. Linkhttps://link.springer.com/article/10.1186/s12903-025-06051-w

Is there an association between periodontal disease and infertility? A systematic review. (2024). ResearchGate. Linkhttps://www.researchgate.net/publication/384880705_Is_there_an_association_between_periodontal_disease_and_infertility_A_systematic_review

Periodontal Disease and Infertility: Probing the Depths of This Potential Connection. (2019). Continuing Education. Linkhttps://cced.cdeworld.com/courses/23488-periodontal-disease-and-infertility-probing-the-depths-of-this-potential-connection

Maternal Infection Research:

The association between periodontal disease and risk of adverse maternal and newborn outcomes: A systematic review and meta-analysis. (2023). Health Science Reports. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10587389/

Effects of different periodontal interventions on the risk of adverse pregnancy outcomes: A systematic review and network meta-analysis. (2024). Frontiers in Public Health. Linkhttps://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1373691/full

Role of periodontal treatment in pregnancy gingivitis and periodontal disease: A systematic review and meta-analysis. (2024). Journal of Maternal-Fetal & Neonatal Medicine. Linkhttps://www.tandfonline.com/doi/full/10.1080/14767058.2024.2416595

Miscarriage Research:

Machado, V., et al. (2022). Periodontitis, female fertility and conception (Review). Biomedical Reports. Linkhttps://www.spandidos-publications.com/10.3892/br.2022.1569

Periodontitis and Infertility: An Evidence-Based Review. (2019). Global Journal of Fertility and Research. Linkhttps://www.reprodgroup.us/articles/GJFR-1-103.php

Premature delivery Research:

Machado, V., et al. (2022). Periodontitis, female fertility and conception (Review). Biomedical Reports. Linkhttps://www.spandidos-publications.com/10.3892/br.2022.1569

Periodontitis and Infertility: An Evidence-Based Review. (2019). Global Journal of Fertility and Research. Linkhttps://www.reprodgroup.us/articles/GJFR-1-103.php

Preterm birth Research:

Machado, V., et al. (2022). Periodontitis, female fertility and conception (Review). Biomedical Reports. Linkhttps://www.spandidos-publications.com/10.3892/br.2022.1569

Periodontitis and Infertility: An Evidence-Based Review. (2019). Global Journal of Fertility and Research. Linkhttps://www.reprodgroup.us/articles/GJFR-1-103.php

Respiratory/Lung

Asthma Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

The association between respiratory diseases and periodontitis: A systematic review and meta-analysis. (2023). Journal of Clinical Periodontology. Linkhttps://onlinelibrary.wiley.com/doi/abs/10.1111/jcpe.13767

Bronchitis Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

COVID-19 complications Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

A systematic review and meta-analysis. (2023). BMC Oral Health. Linkhttps://link.springer.com/article/10.1186/s12903-023-03378-0

Emphysema Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

Lemierre's syndrome Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/ (Note: Rare conditions like Lemierre's may be included in broader infectious respiratory reviews.)

Lung disease Research:

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

a systematic review and meta-analysis. (2023). BMJ Open. Linkhttps://bmjopen.bmj.com/content/13/6/e067432

Association between periodontal disease and chronic obstructive pulmonary disease. (2023). Journal of Dental Sciences. Linkhttps://www.sciencedirect.com/science/article/pii/S1882761623000339

Pneumonia Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

Sinusitis Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

Sleep apnea Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

Tuberculosis Research:

Romandini, M., et al. (2023). Periodontal Health and Disease in the Context of Systemic Diseases. Mediators of Inflammation. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10199803/

Periodontitis and respiratory diseases: A systematic review with meta-analysis. (2020). Oral Diseases. Linkhttps://pubmed.ncbi.nlm.nih.gov/31715080/

Neurological/Brain

Alzheimer's disease Research:

Dominy, S. S., et al. (2019). Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Science Advances. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12283705/

Impact of periodontal disease on cognitive disorders, dementia, and Alzheimer's disease: A systematic review and meta-analysis. (2024). Brain and Behavior. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11336026/

Association between periodontal disease and Alzheimer's disease: A systematic review and meta-analysis. (2024). Frontiers in Aging Neuroscience. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12283705/

Dementia Research:

Influence of periodontal disease on risk of dementia: a systematic literature review and a meta-analysis. (2020). European Journal of Epidemiology. Linkhttps://link.springer.com/article/10.1007/s10654-020-00648-x

Epilepsy/seizures Research:

Pereira, P. A. B., et al. (2021). Is There Any Association Between Neurodegenerative Diseases and Periodontitis? A Systematic Review. Frontiers in Aging Neuroscience. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8180549/

Is There Any Association Between Neurodegenerative Diseases and Periodontitis? A Systematic Review. (2021). Frontiers in Aging Neuroscience. Linkhttps://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2021.651437/full

Memory loss Research:

Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies. (2022). Journal of the American Geriatrics Society. Linkhttps://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.17978

Periodontal Disease and Alzheimer's: Insights from a Systematic Literature Review. (2024). Biotechnology and Genetic Engineering Reviews. Linkhttps://www.sciencedirect.com/science/article/pii/S2274580724000414

Oral Health and Cognitive Decline: A Systematic Review of Longitudinal Studies. (2025). Applied Sciences. Linkhttps://www.mdpi.com/2076-3417/15/12/6728

Association Between Periodontitis and Cognitive Impairment in Adults. (2019). Frontiers in Neurology. Linkhttps://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00323/full

Multiple sclerosis Research:

Parkinson's disease Research:

Stroke Research:

Holmstrup, P., et al. (2017). Comorbidity of Periodontal Disease: Two Sides of the Same Coin? An Introduction for the Clinician. Journal of Periodontology. Linkhttps://www.elsevier.es/en-revista-neurologia-english-edition--495-articulo-the-association-between-periodontitis-cerebrovascular-S217358082400018X?referer=buscador

Cardiovascular/Heart

Angina Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

Periodontitis and Cardiovascular Diseases. Consensus Report. (2020). Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Atherosclerosis Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

Increasing Evidence for an Association Between Periodontitis and Cardiovascular Disease. (2015). Circulation. Linkhttps://www.ahajournals.org/doi/10.1161/circulationaha.115.020869

Atrial fibrillation Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

Bacterial endocarditis Research:

Mapping Review of the Correlations Between Periodontitis, Dental Caries, and Infective Endocarditis. (2024). Frontiers in Cardiovascular Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12110351/

THE ASSOCIATION BETWEEN PERIODONTITIS AND INFECTIVE ENDOCARDITIS. (2024). Journal of the American College of Cardiology. Linkhttps://www.jacc.org/doi/10.1016/S0735-1097%252824%252904151-2

The Effect of Periodontal Disease on Endocarditis. (2025). Brieflands. Linkhttps://brieflands.com/journals/mca/articles/158484

Exploring links between oral health and infective endocarditis. (2024). Frontiers in Oral Health. Linkhttps://www.frontiersin.org/journals/oral-health/articles/10.3389/froh.2024.1426903/full

Congenital heart disease Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

Coronary heart disease Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

An updated meta-analysis of prospective cohort studies. (2015). International Journal of Cardiology. Linkhttps://www.internationaljournalofcardiology.com/article/S0167-5273%2815%2930209-6/abstract

Heart attack Research:

Periodontal disease is associated with the risk of cardiovascular disease independent of sex: A meta-analysis. (2023). Frontiers in Cardiovascular Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10010192/

Periodontal Disease and Atherosclerotic Cardiovascular Disease. (2025). Circulation. Linkhttps://www.ahajournals.org/doi/10.1161/CIR.0000000000001390

Association between Myocardial Infarction and Periodontitis. (2016). Frontiers in Physiology. Linkhttps://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2016.00519/full

Periodontal disease and subsequent risk of cardiovascular outcome and all-cause mortality. (2023). PLOS ONE. Linkhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290545

Heart disease Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

An updated meta-analysis of prospective cohort studies. (2015). International Journal of Cardiology. Linkhttps://www.internationaljournalofcardiology.com/article/S0167-5273%2815%2930209-6/abstract

Peripheral arterial disease Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

Pulmonary embolism Research:

Is periodontal infection a risk factor for thromboembolic disease? A systematic review. (2023). Journal of Indian Society of Periodontology. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10281308/

Periodontitis impacts on thrombotic diseases: from clinical aspect to future therapeutic approaches. (2024). International Journal of Oral Science. Linkhttps://www.nature.com/articles/s41368-024-00325-9

Pulmonary disease and periodontal health: a meta-analysis. (2022). Molecular Medicine Reports. Linkhttps://pubmed.ncbi.nlm.nih.gov/35122603/

Periodontal disease and incident venous thromboembolism: The Atherosclerosis Risk in Communities study. (2018). Journal of Clinical Periodontology. Linkhttps://onlinelibrary.wiley.com/doi/abs/10.1111/jcpe.13029

Rheumatic fever Research:

Sanz, M., et al. (2020). Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. Linkhttps://globalheartjournal.com/articles/10.5334/gh.400

Periodontal Diseases and Heart Diseases: A Systemic Review. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10466634/

Hematologic/Blood

Anemia Research:

Are Adults Over 18 Years of Age with Anaemia More Likely to Have Periodontal Disease? A Systematic Review and Meta-Analysis. (2023). Cureus. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10593371/

Decreased Hemoglobin Concentration and Iron Metabolism Disorder in Periodontitis: Systematic Review and Meta-Analysis. (2019). Frontiers in Physiology. Linkhttps://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2019.01620/full

The tendency of anemia of inflammation in periodontal diseases. (2023). Clinical Science. Linkhttps://portlandpress.com/clinsci/article/137/3/251/232510/The-tendency-of-anemia-of-inflammation-in

Bleeding disorders Research:

Periodontitis and circulating blood cell profiles: a systematic review and meta-analysis. (2021). Experimental Hematology. Linkhttps://www.sciencedirect.com/science/article/pii/S0301472X20305920

Blood hematologic disorders (general) Research:

The Bloody Crossroads: Interactions between Periodontitis and Hematologic Diseases. (2024). International Journal of Molecular Sciences. Linkhttps://www.mdpi.com/1422-0067/25/11/6115

Exploring the Impact of Blood Disorders on Dental Caries. (2023). Cureus. Linkhttps://www.cureus.com/articles/185831-exploring-the-impact-of-blood-disorders-on-dental-caries

An Overview on the Relation Between Blood Disorders, Periodontitis, and Other Oral Conditions. (2025). Alqalam Journal of Medical and Applied Sciences. Linkhttps://journal.utripoli.edu.ly/index.php/Alqalam/article/download/740/622/1432

Thrombocytopenia Research:

Periodontitis and circulating blood cell profiles: a systematic review and meta-analysis. (2021). Experimental Hematology. Linkhttps://www.sciencedirect.com/science/article/pii/S0301472X20305920

Autoimmune/Immune

Acquired neutropenia Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Chronic granulomatous disease Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Granulomatosis with polyangiitis Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Hyperimmunoglobulin E syndromes Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Leukocyte adhesion deficiency syndromes Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Psoriasis Research:

Periodontal Disease in Patients with Psoriasis: A Systematic Review. (2022). Frontiers in Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9516998/

Periodontitis in Psoriasis Patients: Systematic Review & Meta-analysis. (2022). Oral Diseases. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9290533/

Could Periodontitis Aggravate Psoriasis? Systematic Review. (2023). Future Dentistry Journal. Linkhttps://www.mdpi.com/2673-6373/3/1/6

Periodontal disease does not increase the risk of subsequent psoriasis. (2023). Scientific Reports. Linkhttps://www.nature.com/articles/s41598-023-32907-8

Psoriatic arthritis Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Hand to Mouth: A Systematic Review and Meta-Analysis of the Association between Rheumatoid Arthritis and Periodontitis. (2016). Frontiers in Immunology. Linkhttps://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2016.00080/full (Note: Related to arthritic autoimmune conditions.)

Rheumatoid arthritis Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Sjögren syndrome Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Systemic lupus erythematosus (lupus) Research:

Periodontitis and risk of immune-mediated systemic conditions: A systematic review and meta-analysis. (2022). Community Dentistry and Oral Epidemiology. Linkhttps://pubmed.ncbi.nlm.nih.gov/36377800/

Association between Apical Periodontitis and Autoimmune Diseases: A Systematic Review. (2015). Journal of Endodontics. Linkhttps://www.sciencedirect.com/science/article/pii/S0099239925000573

A systematic review and network meta-analysis of the association between systemic antitumor therapy for synchronous cancer and bisphosphonate-related osteonecrosis of the jaw. (2025). BMC Oral Health. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11956190/

Genetic/Syndromes Chédiak-Higashi syndrome Research:

Genetic Biomarkers for Periodontal Diseases: A Systematic Review. (2025). Journal of Personalized Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12286649/

Cohen syndrome Research:

Genetic Biomarkers for Periodontal Diseases: A Systematic Review. (2025). Journal of Personalized Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12286649/

Down syndrome Research:

Efficacy of periodontal treatment modalities in Down syndrome patients: a systematic review and meta-analysis. (2024). Evidence-Based Dentistry. Linkhttps://www.nature.com/articles/s41432-024-01055-x

Genetic Biomarkers for Periodontal Diseases: A Systematic Review. (2025). Journal of Personalized Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12286649/

Ehlers-Danlos syndrome Research:

Genetic Biomarkers for Periodontal Diseases: A Systematic Review. (2025). Journal of Personalized Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12286649/

Epidermolysis bullosa acquisita Research:

Genetic Biomarkers for Periodontal Diseases: A Systematic Review. (2025). Journal of Personalized Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12286649/

Gaucher disease Research:

Genetic Biomarkers for Periodontal Diseases: A Systematic Review. (2025). Journal of Personalized Medicine. Linkhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12286649/

Glycogen storage disease Research:

Papapanou, P. N., et al. (2018). Periodontal manifestations of systemic diseases and

acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions
- https://pubmed.ncbi.nlm.nih.gov/29926943/

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Contact For Speaking

LYNELLE DEROO, RDH, BS

661-917-0404

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Contact For Speaking

LYNELLE DEROO, RDH, BS

661-917-0404

CLICK HERE